Baculovírus como bioinseticidas: Evolução da produção in vivo e perspectivas futuras
DOI :
https://doi.org/10.33837/msj.v9i1.1744Mots-clés :
Controle biológicoRésumé
Os Baculovírus são agentes entomopatogênicos amplamente utilizados no controle biológico de insetos-praga, destacando-se por sua alta especificidade, biossegurança e eficácia. A produção in vivo em larvas hospedeiras permanece uma estratégia relevante devido ao baixo custo e à simplicidade técnica. Esta revisão narrativa analisa criticamente os avanços recentes (2021–2025) nas metodologias de produção in vivo de Baculovírus, incluindo a otimização da criação de hospedeiros, protocolos de infecção, formulações para estabilidade e caracterização molecular. Também são discutidos os progressos na engenharia genética voltada ao aumento da virulência e à produção de proteínas recombinantes, bem como o potencial de mercado e as perspectivas regulatórias. A síntese da literatura recente evidencia tendências tecnológicas e desafios persistentes, como a padronização de processos, escalabilidade e integração com ferramentas computacionais e de automação. Este trabalho fornece uma visão atualizada e abrangente, contribuindo para o desenvolvimento de bioinseticidas mais eficazes e sustentável.
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© Aline Brito Vaz, Márcio da Costa Silva, Tenille Ribeiro Souza, Erasmo Ribeiro da Paz Filho, Eliza Gonçalves Souza, Leonardo Cunha Albuquerque, Nadson Carvalho Pontes 2026

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