Baculoviruses as bioinsecticides: Evolution of in vivo production and future perspectives

Authors

  • Aline Brito Vaz Instituto Federal de Educação, Ciência e Tecnologia Goiano – IF Goiano, Campus Morrinhos, Goiás, Brazil
  • Márcio da Costa Silva Centro de Excelência em Bioinsumos do Estado de Goiás – CEBIO, Goiânia, Goiás, Brazil
  • Tenille Ribeiro Souza Instituto Federal de Educação, Ciência e Tecnologia Goiano – IF Goiano, Campus Morrinhos, Goiás, Brazil
  • Erasmo Ribeiro da Paz Filho Instituto Federal de Educação, Ciência e Tecnologia Goiano – IF Goiano, Campus Morrinhos, Goiás, Brazil
  • Eliza Gonçalves Souza Instituto Federal de Educação, Ciência e Tecnologia Goiano – IF Goiano, Campus Morrinhos, Goiás, Brazil
  • Leonardo Cunha Albuquerque Instituto Federal de Educação, Ciência e Tecnologia Goiano – IF Goiano, Campus Morrinhos, Goiás, Brazil
  • Nadson Carvalho Pontes Instituto Federal de Educação, Ciência e Tecnologia Goiano – IF Goiano, Campus Morrinhos, Goiás, Brazil

DOI:

https://doi.org/10.33837/msj.v9i1.1744

Keywords:

biological control, bioinput, genetic engineering, commercial applications

Abstract

Baculoviruses are entomopathogenic agents widely used in the biological control of insect pests, standing out for their high specificity, biosafety, and efficacy. In vivo production in host larvae remains a relevant strategy due to its low cost and technical simplicity.The present study consists of a narrative review of the scientific literature, with a qualitative and analytical approach, aimed at synthesizing recent advances in the in vivo production of Baculoviruses for use as bioinsecticides. The literature search was conducted in the Scopus, Web of Science, PubMed, and Google Scholar databases, covering publications from january 2021 to march 2025.The synthesis of recent literature highlights technological trends including optimization of host rearing, infection protocols, formulation strategies for stability, and molecular characterization. Advances in genetic engineering aimed at increasing virulence and recombinant protein production are also discussed, as well as market potential, regulatory perspectives, and persistent challenges such as process standardization, scalability, and integration with computational and automation tools.This work provides an updated and comprehensive overview, contributing to the development of more effective and sustainable bioinsecticides.

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Published

2026-05-15

How to Cite

Vaz, A. B., Silva, M. da C., Souza, T. R., Paz Filho, E. R. da, Souza, E. G., Albuquerque, L. C., & Pontes, N. C. (2026). Baculoviruses as bioinsecticides: Evolution of in vivo production and future perspectives. Multi-Science Journal, 9(1), 43–49. https://doi.org/10.33837/msj.v9i1.1744

Issue

Vol. 9 No. 1 (2026): Special Issue - Trends in Bioinputs: Challenges and Opportunities

Section

Agricultural Sciences

License

Copyright (c) 2026 Aline Brito Vaz, Márcio da Costa Silva, Tenille Ribeiro Souza, Erasmo Ribeiro da Paz Filho, Eliza Gonçalves Souza, Leonardo Cunha Albuquerque, Nadson Carvalho Pontes

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